Also, the 300 and 350 cowling's are taller then smaller engines. Even with the fold down transom, it may still hit the cowling when fully tilted, there is a raised lip where the well folds up and down, check clearance here. Regardless, going from twins to singles will need some work to the transom. You are placing more weight over a smaller area, instead of spreading it out, you can't just plug up the old holes and mount a new engine, that would be a mistake that might be costly. If I were ever to consider a 25ft boat with a single, it would be a 350, I would always regret a 300 but it looks like he is bent on going to a single and it is not my boat. I think I would buy used twins or new ones over a big single on that hull. I agree with Bob, 30in shaft would be my recommendation, but check with your local dealer. A 25 inch will likely have trouble in rough conditions and could be a nightmare.