John: My two cents - and that's what it's worth!
When seas get over 2', I find that my 282 is sensitive to wave period, or the space between waves, as much or more than wave height. Wave height can, to some extent, be compensated for with engine trim and trim tabs, as you know. And as Skunkboat said, sometimes in those closely spaced waves, going faster, to get on top of the waves, may give you a better ride. I used to find that helpful at times, but the bad discs in my neck don't like that option so much anymore.
Another option is zig-zagging to effectively increase the wave period. For example, I usually head out the inlet and run about 12 miles south and anywhere from 3-6 miles offshore to set up a drift. And our prevailing summer winds are SSE, pretty much right on my nose. In that situation, to increase spacing between the waves, you can zig-zag your way south. Sometimes running more south, sometimes more east. Just another option you have.
Also, as you're running, watch the waves closely. They usually come in sets. Like maybe sets of 5-7. What I mean is, you may be going along okay and along comes a wave that pounds you. Count out the waves and likely you'll encounter another wave that pounds you again. When you get the pattern down, you'll recognize that wave coming and you'll be able to turn the boat a bit to take it at more of an angle. Once you're over that wave, resume your course knowing you'll be doing the same thing again in 5-7 waves. After a while, you won't need to count, you'll recognize the wave you need to take at more of an angle.
And it can't hurt to find an experienced captain whose willing to go out with you and give some real world instruction.
Rob