I really don't get why removing the tank to reduce weight at the risk of needing fuel, etc. The weight helps with the ride. I have the 52g rear and 150g mid tank for total of 202gallons.
I go anywhere from 30 to 60 out, troll all day and run back. In a couple of cases when 40 out, seas/storm kicked in and took 2 hours to get back. Burned a lot of fuel and was glad I had the reserve as it could have gotten much worse .
As best practice, I never go out unless both tanks are full. I store both tanks full and always use Ring Free Plus and Startron to keep the water at bay. During offseason, I am usually down for about 5-6 months and so far never have any issue with fuel. Seems the Startron keeps it fresh enough to burn through safely for the first tank.
I also start off burning the aft tank down to about 48-50 gallons....the indicator light on helm flashes when it is time to switch tanks, then burn the rest on main tank. I do this to ensure once the transom fish box full of fish/ice/saltwater mix weight is offset by an empty aft tank on the way back. Kind of a tradeoff in the aft weight. Also, this helps keep the normal ride attitude in check.
Grady's like the weight and seem to ride better. I have never noticed a huge difference in fuel savings by shaving off a few pounds. I think it is minimal.