Welcome aboard!
Just a quick comment as you'll get some replies from CC owners here, but the hulls are the same so...
The 22 footer does run quite a bit more $$, but it's a bigger boat all around and will ride a little better in a seaway. It is also heavier so if you're trailering that may be a consideration depending on your tow-rig. Either boat is easy to launch and retrieve. If you're paying moorage they're going to be similar unless you miss a slip size limit and have to go bigger.
The smaller hull does great with an F150, any of the big blocks on the 22 - 200-250. Anything in recent years will have a Yamaha four-stroke, they are reliable, fuel efficient, and quiet (at idle, anyway!).
Were you looking a new, or resale? Lots better buys out there on the latter, but some guys just like to buy new stuff.
In new or used, equipment and accessories are expensive, so the better fit-out, the less you'll have to spend setting it up the way you want it. An electronics package can easily run into a few grand, depending on what you need/want. A T-top can be added to either one, so if you find one without you can have one built the way you like it.
You didn't say if you had owned boats, or Grady's in the past, but in any case they are a terrific product, good components, very nicely designed, and very well respected in the boating community. The owners here just love their boats!
Let us know what you find...and good luck!