Islander 270 purchased new in March 2002 with single 250HP OX66. Put 465 hrs on it by Nov 2005, then repowered with twin F150's.
The OX66 was strong, thirsty, reliable, loud, thirsty (yes).... Cruise at 4000RPM was about 22-24kts, getting about 1.2-1.3nmpg. WOT RPM was 5400-5500, at approx 30.5kts, sucking 28gph. Oil use averaged 1gal/33gal fuel for the entire life. Thought about having it made a bit 'leaner', but that can be risky.
The OX66 had no problem spinning a Yamaha SWS 15.25"x17", but there was always excessive prop slip. Went to a PowerTech OFS4 x 17", kept good RPM, and improved "bite" and mid-range performance a bit. Slippage decreased, but still high.
GW never agreed, but I think a single on this boat suffers from aerated (i.e. disturbed) water aft of the two scoop injections mounted just off centerline a couple of feet forward of the transom.
You didn't ask about performance with the F150's, so I won't make you feel bad. I will tell you that we repowered so we would have the range to fish offshore safely - we make 75nm (each way) trips to the Norfolk Canyon with no problem, and we couldn't do that with the OX66.
BTW, our boat is bottom painted, hardtop with curtains almost always up, and performance numbers under real world, loaded conditions.
Finally, we have almost 1000hrs on the twins now, so we do use our boat a lot.
Brian