Chris - good point about engine height. I think it would have be quite far off to experience that consumption difference...
Yes, thats what i believe too but maybe the combination of too deep and other factors, however i don't believe that the new 4 strokes burn 40% or the 50 gallons OP wrote more, thats virtually impossible and gauges show correct fuel burn. Not sure what kind of gauges OP has, but all newer outboards calculate fuel flow by counting injector cycles and that is very accurate, very! If Op has the old impeller driven Yamaha fuel Flow Sensors or a 3rd party fuel flow metering device the problem could be there, or OP has by mistake set the fuel gauge calibration to a totally wrong value.
Honestly i believe that there is a error in OP's GuessTimating about fuel consumption, either gasoline was stolen or a trip forgotten.
I would exclude a fuel leak as the smell would be very noticeable and where should go 50 gallons of fuel?
One thing what could be is that the new propellers are way to small in pitch and/or diameter or damaged and OP has to run 6000 rpm for same speed he could reach with the old engines before, that would explain burning 40% more fuel
His boat is out of the water, so nothing really useful (particular rpm-speed-fuel flow) could be done to verify a hypothetic 40% higher fuel flow, what would be helpful is
- model and year of Yamaha 250HP
- kind of gauges are installed
- kind of gauge showing fuel flow
- verifying if fuel flow calibration is set correctly
- pulling all spark plugs and check for heavy fouling
- a photo from side and height as AV Plates side using a ruler or similar attached to hull to show most exactly where AV plates are
- double check if new engines are same length as the previous ones, same hole on 5" longer model would make LU sitting ways too deep
- checking for gas smell in bilge
- thinking again and once more if there is a error in OP's fuel burn calculation, possibility of fuel theft or incorrect fuel pump
Chris