I don't fish, so I'll leave the angling advice to Halfhitch.
The Passes:
Avoid New Pass; It shoals severely. This is the pass separating Lido Beach from Longboat Key.
Check with the Sarasota Yacht Club for the latest info on Big Sarasota Pass, which separates Lido from Siesta Key. They have floating ATON's that they move regularly when new soundings are taken. I believe, although I'm not sure, that their website has the latest navigational info. This pass is suspect as well. I followed the floating aids in once and went to 2 feet.
I have noticed you enjoy anchoring as well. As you head out toward Big Sarasota Pass, you'll find really cool tidal islands to your stbd before you reach open water. That channel thru there, until you get to the Gulf is 15-20 feet deep due to the strong tidal action. You'll be carrying the green's on your stbd side, obviously, and just inside Green "13" if memory serves, is some great anchoring. Bow & stern anchors are helpful there as the tide roars out that pass like the Colorado River.
Your Seafarer draws a little less than our Marlin..The first time or two, slow down and trim up 'till you get reliable tracks on your chartplotter thru Big Sarasota Pass..
Venice Inlet is always deep; you probably won't travel that far South, but Stump Pass near Englewood is suspect as well. They dredge it, it fills in. They dredge it....
Longboat Pass, at the North end of Longboat Key, is the same shoaling story. It may be navigable, but approach carefully. Big-time current in there as well.
I vacationed on Longboat half my life. I literally grew up boating in that area. I don't know whether this is your kind of fishing, but a friend of my parents had a boat in Whittaker Bayou, just North of Van Wezel on the East shore of Sarasota Bay. We would motor out of that bayou, head North for 1/4 mile or so and drift over the weed beds, several hundred yards off the shore. We used live shrimp and would catch speckled trout, jacks, the occasional flounder and sometimes a "Sailcat." (A catfish with a dorsal straight up out of his head, like the mast of a sail.) Again, I don't know much about fishing, but I thought I'd throw this out.
Have Parth show you around Lake Lanier while you two are partying...