Get one of these and stop and check temps periodically, trust me it's worth it.
He's only going 110 miles, which even if he only had 20 gallons of fuel in the tank and was only getting 6 mpg then he'd still have enough to get him back without having to stop along the way for fuel. 220 total miles roundtrip shouldn't be any issue for a pickup truck with a full fuel tank, even if he's only getting 8-10 mpg or similar.5 - stop for gas long before you need it, because sometimes "easy in/out" gas stations are hard to find and you don't want to be trying to move in tight quarters
I'd gladly trade you that for what I had to do last October, which was a 3009 mile trek from Maryland to the Seattle area where I live, after buying my 228 Seafarer out there. This time coming back there weren't any issues and it took 4.5 days to do the trek, of which most days I put in around 600 miles or so of driving, although the second to last day I drove 850 miles. The first boat I ever purchased on my own was actually out in Maryland as well, and I drove roundtrip from Seattle to Maryland and back in 7 days. Two of the days I put in 1200 miles a day of driving and with it being spring, as well as lighter out earlier and later, you could do each leg of the trip per day. Although, that is a lot of hours driving and towing a boat behind you as well. But it can definitely be done if you started at say 6 am and drove until 9 or 9:30 pm and made minimal stops. Fortunately, I think all but maybe a couple of hours of that drive would also be during daylight hours as well. Good luck!I've got to make 2 trips 1100 miles each way this year since I added a Grady to the mix. Lake Wales FL to Greenbackville VA. 14 hours driveway to driveway. Hope diesel keeps edging downward.